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Table 4 Univariate analysis for association of clinical parameters with existence of circadian rhythmicities in PR in Period 1.

From: Emergence of physiological rhythmicity in term and preterm neonates in a neonatal intensive care unit

Clinical variables

Cycle 1440 (n = 20)

≤ 720 (n = 80)

p

Gestational age (wks)

32.7 ± 4.9

34.2 ± 4.6

NS

Birth weight (g)

1930 ± 983

2077 ± 900

NS

Apgar Score < 6 (5 min)

1 (5)

10 (12.7)

NS

Asphyxia

4 (20)

17 (21.3)

NS

RDS

4 (20)

14 (17.3)

NS

IUGR

3 (15)

6 (7.5)

NS

Mean of variables

   

   Mean PR (/min)

140.2 ± 8.6

135.5 ± 12.8

NS

   Mean RR (/min)

45.7 ± 8.5

43.0 ± 8.5

NS

   Mean SpO2 (%)

97.9 ± 1.1

97.9 ± 1.3

NS

Treatment of data sampling

   

   Oxygenation

18 (90)

46 (57.5)

0.02

   Intubation

10 (50)

25 (31.3)

NS

   Aminophylline

1 (5)

4 (5)

NS

   Phenobarbital

0 (0)

1 (1.3)

NS

   Midazolam

3 (15)

6 (7.5)

NS

  1. Data are expressed as mean ± SD or n (%). Mann-Whitney U test was performed for continuous variables and Fisher's exact test was performed for categorical variables.