Table 1 Circadian parameters for R_w and T_b(mean ± SEM) and serum melatonin for each animal tested. Animals in which the circadian rhythm of serum melatonin was desynchronized from R_w and T_b, are indicated in bold. Animals in which the serum melatonin rhythm was damped are indicated in italic. (Amp. = amplitude)

0.6 ± 0.2

19.3 ± 3.1

25.4

37.2 ± 0.1

2.1 ± 0.2

25.4

26–559.

0.7 ± 0.1

19.3 ± 3.1

25.1

36.8 ± 0.1

1.8 ± 0.2

25.0

12–122

0.1 ± 0.1

5.6 ± 1.2

24.6

37.0 ± 0.1

1.9 ± 0.2

24.6

10–146

NS

NS

12–544

6.6 ± 1.9

45.6 ± 2.1

25.1

37.6 ± 0.1

2.8 ± 0.2

25.2

105–204

2.6 ± 0.7

39.7 ± 5.0

24.3

37.5 ± 0.2

1.9 ± 0.2

24.3

38–306

3.4 ± 1.1

30.8 ± 3.1

24.4

36.9 ± 0.2

1.7 ± 0.1

24.4

109–204

0.4 ± 0.1

8.3 ± 3.4

25.0

38.5 ± 0.1

2.1 ± 0.4

25.1

32–206

3.3 ± 0.8

48.8 ± 7.7

25.3

37.3 ± 0.1

2.3 ± 0.2

25.2

138–188

0.5 ± 0.1

12.2 ± 2.0

24.3

36.8 ± 0.1

1.8 ± 0.1

24.4

108–358

6.0 ± 1.3

53.5 ± 5.2

25.1

37.6 ± 0.2

2.4 ± 0.4

25.1

128–572

1.3 ± 0.2

23.5 ± 6.1

25.2

37.4 ± 0.1

1.8 ± 0.2

25.2

158–354

0.4 ± 0.1

8.9 ± 1.1

25.1

37.1 ± 0.1

1.6 ± 0.2

25.1

97–707

0.7 ± 0.1

15.6 ± 1.3

25.2

37.3 ± 0.1

2.1 ± 0.2

25.1

144–238

0.9 ± 0.2

15.1 ± 1.4

24.6

37.5 ± 0.1

2.1 ± 0.2

24.5

118–566

1.2 ± 0.3

24.7 ± 4.0

25.1

37.6 ± 0.1

2.3 ± 0.6

25.2

155–278

0.6 ± 0.1

14.8 ± 3.1

24.3

37.2 ± 0.1

1.5 ± 0.3

24.2

26–113

1.1 ± 0.6

15.9 ± 2.8

25.0

37.4 ± 0.1

2.0 ± 0.5

25.0

20–423

0.7 ± 0.1

15.8 ± 2.5

24.5

37.7 ± 0.1

2.0 ± 0.2

24.4

20–104

1.0 ± 0.2

16.1 ± 1.3

24.5

37.6 ± 0.1

1.9 ± 0.4

24.5

21–120

1.1 ± 0.1

20.7 ± 1.9

25.4

37.4 ± 0.1

2.1 ± 0.2

25.4

27–295

0.7 ± 0.1

13.7 ± 1.5

25.1

37.4 ± 0.1

1.9 ± 0.2

25.1

34–559