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Table 1 Effect of PER 2 and CRY 2 on the cell cycle of MCF-7 cells

From: Period-2: a tumor suppressor gene in breast cancer

 

G1

S

G2/M

GFP

7414

15.57

10.29

pCS2

65.36

18.03

16.61

PER2

82.24

7.16

10.60

pCS2 + pcDNA3.1

62.61

17.49

19.90

PER2 + CRY2

89.19

0.58

10.22

  1. Cell cycle analyses were conducted on parental, vector-transfected, PER 2 overexpressing MCF-7 cells, CRY 2 overexpressing MCF-7 cells, and cells over expressing both PER 2 and CRY 2. After three days of expression, propidium iodide(PI) staining and samples were analyzed by flow cytometry.