Figure 5

Example of model fit (Tibolone group). Examples of estimated model components belonging to an animal of the Tibolone group, separated by experimental phase (P₁ to P₃). (a) Tail skin temperature time measurements (y _n ); (b) circadian components ; (c) amplitude functions ; (d) trend curves ; (e) combination of estimated circadian components and trend curves , embedded in the time series. Daytime periods are shown in yellow; nighttime periods are shown in blue. The model parameter estimates are given in the Tables 1 and 2.