Figure 1

Locomotor activity and clock period. (A) Representative locomotor activity records of wild-type (wt) (left panel) and synaptophysin knock-out (Syp ^-/-) male mice (right panel). Black and white bars on top of the plots indicate the 12 h light: 12 h dark cycle (LD). The grey shaded areas filling the panels in the lower part indicate constant darkness (DD). Below the locomotot activity records χ²-periodogram analysis is shown indicating the period length. (B) Period is similar in wild-type (n=17) and Syp ^-/- male mice (n=18). (C) Total activity is comparable between the two genotypes. (D) Precision of activity onset is comparable between the two genotypes.