Figure 2

Response to light pulses in nude and WT mice. Athymic nude and control WT mice were subjected to light pulses during the early night (A, B) or the late night (C). A. Representative actograms of general activity of nude and WT mice receiving a light pulse (150 lux, 10 min) at CT15 (Right). No significant difference was found between the two strains (Left, mean ± SEM, -23.2 ± 6.2 min in nude and −20.2 ± 6.0 min in WT mice, n = 6, p > 0.05, Student’s t test). B. Representative actograms of nude and WT mice receiving a light pulse (150 lux, 120 min) at CT14 (Right). No significant difference was found between the two strains (Left, mean ± SEM, -99 ± 6.3 min in nude and −161.3 ± 29.3 min in WT mice, n = 3, p > 0.05, Mann Whitney test). C. Representative actograms of nude and WT mice receiving a light pulse (150 lux, 10 min) at CT22 (Right). No significant difference was found between the two strains (Left, mean ± SEM, 42 ± 31 minutes for nude and 2 ± 12 for WT mice, n = 3, p > 0.05, Mann Whitney test).