Diurnal and nutritional adjustments of intracellular Ca2+ release channels and Ca2+ ATPases associated with restricted feeding schedules in the rat liver

Table 1 Daily rhythm characteristics of plasma corticosterone and PER1 from rats under free access meal and restricted schedule determined by COSINOR test

	Acrophase ZT (h)		Amplitude		MESOR		Rhythmicity ( *P < 0.05* )
	AL	RF	AL	RF	AL	RF	AL	RF
Corticosterone	09:30 ± 00:26	02:15 ± 00:35*	3.13 ± 0.23	3.39 ± 0.30	17.6 ± 3.9	20.7 ± 4.3	0.005	0.6^NS
PER1 (WB)	17:30 ± 00:19	05:06 ± 00:24*	0.27 ± 0.015	0.22 ± 0.011	0.55 ± 0.07	0.64 ± 0.06	0.002	0.04

The Acrophase, amplitude, and MESOR as well as the rhythmicity significance were determined as described in the Methods section. The values were determined from the diurnal profiles of these parameters. The units corresponding to amplitude and MESOR are mg/dl (corticosterone) and normalized units (PER1/ACTIN Western Blot). * (p < 0.05) significant between AL vs RF (Student´s t-test). Not significant 24 h rhythmicity was designed as NS.