Figure 3

Average time of activity onset during LD cycles. The average time of activity onset over 14 days before ZT12 was measured for wildtype, Per1 ^−/−, Pml ^−/−, Per1 ^−/− /Pml ^−/− and Per2 ^−/− /Pml ^−/− mice. Activity onset for Per2 ^−/− and Per1 ^−/− mice was previously reported by Spoelstra et al., 2004. Error bar indicates SEM. *p < 0.05, (n = 6).