|  | Baseline | Study End (3 months) | % change | Unpaired t test (df = 67) | Paired t test (df = 22) | Paired t test (df = 45) | Unpaired t test (df = 67) | |||
---|---|---|---|---|---|---|---|---|---|---|---|
Item No. | Description | Control (n = 23) | Intervention (n = 46) | Control (n = 23) | Intervention (n = 46) | Control | Intervention | Baseline comparison | Control change | Intervention change | 3 month comparison |
 |  | mean (SD) | mean (SD) | mean (SD) | mean (SD) |  |  | t statistic | t statistic | t statistic | t statistic |
1 | Fatigue/tiring easily? | 2.9 (0.9) | 2.9 (1.1) | 2.7 (1.1) | 2.1 (1.0) | 7.6 | 26.9 | -0.16 | 0.93 | 4.04** | 1.76 |
2 | Trouble concentrating | 2.5 (1.1) | 2.9 (1.2) | 2.5 (0.9) | 1.8 (0.9) | 1.7 | 36.8 | -1.23 | 0.21 | 5.84** | 3.46* |
3 | Physical clumsiness? | 2.0 (1.1) | 1.7 (1.0) | 1.6 (0.6) | 1.5 (0.9) | 21.7 | 13.7 | 1.02 | 1.93 | 1.48 | -0.70 |
4 | Decreased daytime alertness? | 2.7 (1.1) | 2.5 (1.2) | 2.1 (0.8) | 1.8 (0.8) | 21.0 | 28.1 | 0.74 | 2.73 | 3.96** | 0.45 |
5 | Trouble with memory? | 2.4 (1.3) | 1.9 (1.1) | 2.1 (0.8) | 1.5 (0.7) | 12.5 | 21.3 | 1.65 | 1.07 | 2.80 | 0.38 |
6 | General feelings of weakness | 2.0 (1.1) | 2.0 (1.0) | 1.7 (0.7) | 1.4 (0.8) | 17.0 | 26.7 | 0.33 | 1.56 | 3.60* | 0.67 |
7 | Light-headed & dizzy | 2.2 (1.4) | 2.1 (1.3) | 2.0 (1.1) | 1.4 (0.8) | 9.8 | 33.7 | 0.26 | 1.10 | 4.04** | 1.74 |
8 | Lethargy/sluggish feelings? | 3.0 (1.0) | 2.7 (1.3) | 2.3 (0.8) | 1.8 (0.8) | 23.5 | 31.7 | 0.93 | 3.43* | 5.07** | 0.55 |
9 | Sleepiness in day | 3.0 (1.2) | 2.8 (1.2) | 2.6 (1.0) | 1.9 (0.7) | 14.5 | 31.0 | 0.66 | 2.47 | 4.90** | 1.55 |
10 | Work performance | 7.0 (1.7) | 6.4 (1.5) | 7.3 (1.6) | 7.6 (1.4) | 4.4 | 19.4 | 1.45 | -1.16 | -6.07** | -2.72 |
11 | Alertness and concentration | 6.2 (1.8) | 6.1 (1.9) | 6.8 (1.7) | 7.5 (1.8) | 9.9 | 22.9 | 0.23 | -2.13 | -4.34** | -1.57 |
 | Combined Score (first 9 items) | 22.7 (7.5) | 21.5 (8.3) | 19.5 (5.2) | 15.4 (5.7) | 14.3 | 28.6 | 0.59 | 2.60 | 5.22** | 1.53 |