Table 1 Genotypes and allele frequencies.
From: NPAS2 and PER2 are linked to risk factors of the metabolic syndrome
Gene | SNPa | Mutation Type | Allele 1b | Allele 2 | n 1 (freq)C | n 2 (freq) | n 11 (freq) | n12 (freq) | n 22 (freq) |
|---|---|---|---|---|---|---|---|---|---|
Acads | rs1799958 | missense | G | A | 768 (0.74) | 266 (0.26) | 283 (0.55) | 202 (0.39) | 32 (0.06) |
Ada | 22G>A | missense | G | A | 978 (0.95) | 56 (0.05) | 461 (0.89) | 56 (0.11) | 0 |
Adcyap1 | rs2856966 | missense | A | G | 850 (0.82) | 184 (0.18) | 344 (0.67) | 162 (0.31) | 11 (0.02) |
Arntl | rs6486120 | intronic | G | T | 744 (0.72) | 290 (0.28) | 280 (0.54) | 184 (0.36) | 53 (0.10) |
rs1982350 | intronic | G | A | 587 (0.57) | 447 (0.43) | 181 (0.35) | 225 (0.44) | 111 (0.21) | |
rs3816360 | intronic | C | T | 552 (0.53) | 482 (0.47) | 152 (0.29) | 248 (0.48) | 117 (0.23) | |
rs2278749 | intronic | C | T | 823 (0.80) | 211 (0.20) | 328 (0.63) | 167 (0.32) | 22 (0.04) | |
rs2290035 | intronic | A | T | 595 (0.58) | 439 (0.42) | 175 (0.34) | 245 (0.47) | 97 (0.19) | |
Arntl2 | rs7958822 | intronic | G | A | 560 (0.54) | 474 (0.46) | 147 (0.28) | 266 (0.51) | 104 (0.20) |
rs4964057 | intronic | T | G | 601 (0.58) | 433 (0.42) | 178 (0.34) | 245 (0.47) | 94 (0.18) | |
rs1037921 | missense | A | G | 947 (0.92) | 87 (0.08) | 433 (0.84) | 81 (0.16) | 3 (0.01) | |
rs2306074 | intronic | T | C | 668 (0.65) | 366 (0.35) | 213 (0.41) | 242 (0.47) | 62 (0.12) | |
rs35878285 | mis-sense | A | 1034 (1.00) | 517(1.00) | |||||
Clock | rs2412646 | intronic | C | T | 760 (0.74) | 274 (0.26) | 280 (0.54) | 200 (0.39) | 37 (0.07) |
rs11240 | intronic | C | G | 696 (0.67) | 338 (0.33) | 227 (0.44) | 242 (0.47) | 48 (0.09) | |
rs2412648 | intronic | T | G | 654 (0.63) | 380 (0.37) | 210 (0.41) | 234 (0.45) | 73 (0.14) | |
rs3805151 | intronic | T | C | 613 (0.59) | 421 (0.41) | 183 (0.35) | 247 (0.48) | 87 (0.17) | |
Cry2 | rs2863712 | missense | T | 1034 (1.00) | 517(1.00) | ||||
Drd2 | rs1800497 | missense | G | A | 838 (0.81) | 196 (0.19) | 336 (0.65) | 166 (0.32) | 15 (0.03) |
rs6277 | silent | G | A | 542 (0.52) | 492 (0.48) | 141 (0.27) | 260 (0.50) | 116 (0.22) | |
Fdft1 | rs11549147 | missense | A | G | 944 (0.91) | 90 (0.09) | 431 (0.83) | 82 (0.16) | 4 (0.01) |
Glo1 | rs2736654 | missense | T | G | 662 (0.64) | 372 (0.36) | 207 (0.40) | 248 (0.48) | 62 (0.12) |
Opn4 | rs1079610 | missense | T | C | 714 (0.69) | 320 (0.31) | 246 (0.48) | 222 (0.43) | 49 (0.09) |
Ncoa3 | rs6094752 | missense | C | T | 1003 (0.97) | 31 (0.03) | 486 (0.94) | 31 (0.06) | 0 |
rs2230782 | missense | G | C | 932 (0.9) | 102 (0.1) | 422 (0.82) | 88 (0.17) | 7 (0.01) | |
rs2230783 | missense | T | 1034 (1.00) | 517(1.00) | |||||
Npas2 | rs11541353 | missense | C | T | 859 (0.83) | 175 (0.17) | 358 (0.69) | 143 (0.28) | 16 (0.03) |
rs2305160 | missense | G | A | 727 (0.7) | 307 (0.3) | 252 (0.49) | 223 (0.43) | 42 (0.08) | |
Npy | rs16139 | missense | T | C | 956 (0.92) | 78 (0.08) | 444 (0.86) | 68 (0.13) | 5 (0.01) |
Per2 | rs934945 | missense | C | T | 917 (0.89) | 117 (0.11) | 402 (0.78) | 113 (0.22) | 2 (0.004) |
10870 | intronic | A | G | 854 (0.83) | 180 (0.17) | 350 (0.68) | 154 (0.30) | 13 (0.03) | |
rs2304672 | UTR 5' | G | C | 865 (0.84) | 169 (0.16) | 361 (0.70) | 143 (0.28) | 13 (0.03) | |
S662G | missense | T | 1034 (1.00) | 517(1.00) | |||||
Plcb4 | rs6077510 | missense | A | G | 552 (0.53) | 482 (0.47) | 142 (0.27) | 268 (0.52) | 107 (0.21) |
Timeless | rs2291739 | missense | A | G | 624 (0.6) | 410 (0.4) | 193 (0.37) | 238 (0.46) | 86 (0.17) |
rs2291738 | intronic | C | T | 546 (0.53) | 488 (0.47) | 147 (0.28) | 252 (0.49) | 118 (0.23) | |
Vip | rs3823082 | intronic | C | T | 854 (0.83) | 180 (0.17) | 351 (0.68) | 152 (0.29) | 14 (0.03) |
rs688136 | UTR 3' | T | C | 676 (0.65) | 358 (0.35) | 221 (0.43) | 234 (0.45) | 62 (0.12) | |
Vipr2 | rs885863 | UTR 3' | T | C | 518 (0.50) | 516 (0.50) | 126 (0.24) | 266 (0.51) | 125 (0.24) |