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Table 1 Genotypes and allele frequencies.

From: NPAS2 and PER2 are linked to risk factors of the metabolic syndrome

Gene SNPa Mutation Type Allele 1b Allele 2 n 1 (freq)C n 2 (freq) n 11 (freq) n12 (freq) n 22 (freq)
Acads rs1799958 missense G A 768 (0.74) 266 (0.26) 283 (0.55) 202 (0.39) 32 (0.06)
Ada 22G>A missense G A 978 (0.95) 56 (0.05) 461 (0.89) 56 (0.11) 0
Adcyap1 rs2856966 missense A G 850 (0.82) 184 (0.18) 344 (0.67) 162 (0.31) 11 (0.02)
Arntl rs6486120 intronic G T 744 (0.72) 290 (0.28) 280 (0.54) 184 (0.36) 53 (0.10)
  rs1982350 intronic G A 587 (0.57) 447 (0.43) 181 (0.35) 225 (0.44) 111 (0.21)
  rs3816360 intronic C T 552 (0.53) 482 (0.47) 152 (0.29) 248 (0.48) 117 (0.23)
  rs2278749 intronic C T 823 (0.80) 211 (0.20) 328 (0.63) 167 (0.32) 22 (0.04)
  rs2290035 intronic A T 595 (0.58) 439 (0.42) 175 (0.34) 245 (0.47) 97 (0.19)
Arntl2 rs7958822 intronic G A 560 (0.54) 474 (0.46) 147 (0.28) 266 (0.51) 104 (0.20)
  rs4964057 intronic T G 601 (0.58) 433 (0.42) 178 (0.34) 245 (0.47) 94 (0.18)
  rs1037921 missense A G 947 (0.92) 87 (0.08) 433 (0.84) 81 (0.16) 3 (0.01)
  rs2306074 intronic T C 668 (0.65) 366 (0.35) 213 (0.41) 242 (0.47) 62 (0.12)
  rs35878285 mis-sense A   1034 (1.00)   517(1.00)   
Clock rs2412646 intronic C T 760 (0.74) 274 (0.26) 280 (0.54) 200 (0.39) 37 (0.07)
  rs11240 intronic C G 696 (0.67) 338 (0.33) 227 (0.44) 242 (0.47) 48 (0.09)
  rs2412648 intronic T G 654 (0.63) 380 (0.37) 210 (0.41) 234 (0.45) 73 (0.14)
  rs3805151 intronic T C 613 (0.59) 421 (0.41) 183 (0.35) 247 (0.48) 87 (0.17)
Cry2 rs2863712 missense T   1034 (1.00)   517(1.00)   
Drd2 rs1800497 missense G A 838 (0.81) 196 (0.19) 336 (0.65) 166 (0.32) 15 (0.03)
  rs6277 silent G A 542 (0.52) 492 (0.48) 141 (0.27) 260 (0.50) 116 (0.22)
Fdft1 rs11549147 missense A G 944 (0.91) 90 (0.09) 431 (0.83) 82 (0.16) 4 (0.01)
Glo1 rs2736654 missense T G 662 (0.64) 372 (0.36) 207 (0.40) 248 (0.48) 62 (0.12)
Opn4 rs1079610 missense T C 714 (0.69) 320 (0.31) 246 (0.48) 222 (0.43) 49 (0.09)
Ncoa3 rs6094752 missense C T 1003 (0.97) 31 (0.03) 486 (0.94) 31 (0.06) 0
  rs2230782 missense G C 932 (0.9) 102 (0.1) 422 (0.82) 88 (0.17) 7 (0.01)
  rs2230783 missense T   1034 (1.00)   517(1.00)   
Npas2 rs11541353 missense C T 859 (0.83) 175 (0.17) 358 (0.69) 143 (0.28) 16 (0.03)
  rs2305160 missense G A 727 (0.7) 307 (0.3) 252 (0.49) 223 (0.43) 42 (0.08)
Npy rs16139 missense T C 956 (0.92) 78 (0.08) 444 (0.86) 68 (0.13) 5 (0.01)
Per2 rs934945 missense C T 917 (0.89) 117 (0.11) 402 (0.78) 113 (0.22) 2 (0.004)
  10870 intronic A G 854 (0.83) 180 (0.17) 350 (0.68) 154 (0.30) 13 (0.03)
  rs2304672 UTR 5' G C 865 (0.84) 169 (0.16) 361 (0.70) 143 (0.28) 13 (0.03)
  S662G missense T   1034 (1.00)   517(1.00)   
Plcb4 rs6077510 missense A G 552 (0.53) 482 (0.47) 142 (0.27) 268 (0.52) 107 (0.21)
Timeless rs2291739 missense A G 624 (0.6) 410 (0.4) 193 (0.37) 238 (0.46) 86 (0.17)
  rs2291738 intronic C T 546 (0.53) 488 (0.47) 147 (0.28) 252 (0.49) 118 (0.23)
Vip rs3823082 intronic C T 854 (0.83) 180 (0.17) 351 (0.68) 152 (0.29) 14 (0.03)
  rs688136 UTR 3' T C 676 (0.65) 358 (0.35) 221 (0.43) 234 (0.45) 62 (0.12)
Vipr2 rs885863 UTR 3' T C 518 (0.50) 516 (0.50) 126 (0.24) 266 (0.51) 125 (0.24)
  1. a) dbSNP symbols http://www.ncbi.nlm.nih.gov/SNP
  2. b) Alleles extracted from HapMap http://www.HapMap.org
  3. c) Total number of alleles in study sample, frequencies in parenthesis.