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Table 2 The Sample sets used.

From: CLOCK is suggested to associate with comorbid alcohol use and depressive disorders

Sample sets

Cases

number n

Controls

number n

1. Depression or Dysthymia + AUD diagnosis vs

individuals without psychiatric symptoms

76

517

2. Individuals with an AUD diagnosis vs

individuals without psychiatric symptoms

446

517

3. Depression or Dysthymia + AUD diagnosis vs

individuals with and without an AUD diagnosis

76

963

  1. The SNPs found nominally associated (P < 0.05) in Sample set 1 were investigated in Sample sets 2 and 3.