Table 4 The 19 circadian clockwork related genes and the 32 SNPs analyzed.
From: CLOCK is suggested to associate with comorbid alcohol use and depressive disorders
Gene | Gene name | Location | ID (rs#) of SNPs genotyped |
|---|---|---|---|
ARNTL | Aryl hydrocarbon receptor nuclear translocator-like | 11p15.2 | (rs2290035, rs3816360, rs2278749) |
ARNTL2 | Aryl hydrocarbon receptor nuclear translocator-like 2 | 12p12.2-p11.2 | (rs4964057, rs2306074, rs7958822, rs1037921) |
CLOCK | Clock homolog (mouse) | 4q12 | (rs3805151, rs2412648, rs11240, rs2412646) |
NPAS2 | Neuronal PAS domain protein 2 | 2q11.2 | (rs11541353, rs2305160) |
PER2 | Period homolog 2 (Drosophila) | 2q37.3 | (Spanagel/10870, rs2304672) |
TIMELESS | Timeless homolog (Drosophila) | 12q13.2 | (rs2291739, rs2291738) |
ACADS | Acyl-Coenzyme Adehydrogenase, C-2 to C-3 short chain | 12q22-qter | (rs1799958/rs17848088) |
ADA | Adenosine deaminase | 20q12-q13.11 | (Asp8Asn) |
ADCYAP1 | Adenylate cyclase activating polypeptide 1 (pituitary) | 18p11.32 | (rs2856966) |
DRD2 | Dopamine receptor D2 | 11q23.1 | (rs6277) |
ANKK1 | Ankyrin repeat and kinase domain containing 1 | 11q23.1 | (rs1800497) |
FDFT1 | Farnesyl-diphosphate farnesyltransferase 1 | 8p23.1-p22 | (rs11549147) |
GLO1 | Glyoxalase I | 6p21.3-p21.1 | (rs2736654) |
OPN4 | LIM domain binding 3;opsin 4 (melanopsin) | 10q23.2 | (rs1079610) |
NCOA3 | Nuclear receptor coactivator 3 | 20q13.12 | (rs6094752, rs2230782) |
NPY | Neuropeptide Y | 7p15.1 | (rs16139) |
PLCB4 | Phospholipase C, beta 4 | 20p12 | (rs6077510) |
VIP | vasoactive intestinal peptide | 6q25.2 | (rs3823082, rs688136) |
VIPR2 | Vasoactive intestinal peptide receptor 2 | 7q36.3 | (rsS885863) |