Table 1 Wheel-running activity recordings. Both alpha and phase shifts indicated are calculated relative to endogenous free-running period.

	Group		P
	Wild-type	Mutants
Alpha in LD (h)	11.35 ± 0.62	12.12 ± 0.21	ns
Phase angle in LD (min)	-49 ± 23.15	9.4 ± 2.92	0.04
Free-running period (h)
Before light pulse	23.57 ± 0.11	23.93 ± 0.03^†	0.01
After light pulse	23.57 ± 0.10	24.02 ± 0.03^†	0.002
Alpha in DD (circadian h)	12.35 ± 0.38	14.88 ± 0.88	0.04
Amplitude in DD (%)	97.3 ± 0.9	97.4 ± 0.5	ns
Amplitude/Alpha (%/h)	7.90 ± 0.27	6.62 ± 0.35	0.03
Phase delays in response to LP at CT15 (circadian h)	1.90 ± 0.34	2.92 ± 0.26	0.04
Reentrainment to 6 h advance of LD cycle (days)	8.7 ± 0.3	8.2 ± 0.4	ns
Reentrainment to 6 h delay (days)	2.0 ± 0.6	2.4 ± 0.4	ns

Phase angle in LD refers to the difference between the time of lights off and activity onset (negative values indicate animals start running before lights off). All data are expressed as Mean ± SEM. P values correspond to Student's t test. ^† Difference between these two results is not significant according to paired t test analysis.