Figure 2
From: Time-of-day dependence of neurological deficits induced by sodium nitroprusside in young mice
Variations of ataxia according to the dosing time of sodium nitroprusside in four-week old male and female mice. The three panels refer to three doses: 3 (a), 3.3 (b) and 3.6 mg.kg-1 (c). Values are the mean ± SEM of four independent experiments. The black bar corresponds to the dark period. Maximums of motor incoordination correspond, irrespective to the gender and dose, to drug dosing at 1 and 13 HALO. χ2 test validated a statistically significant difference according to dosing-time in both genders (P < 0.0004). No statistically significant rhythm was detected by Cosinor analysis with correction for multiple testing.