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Table 2 Parameters of ultradian and circadian rhythms of sodium nitroprusside-induced motor incoordination in 4 week old mice

From: Time-of-day dependence of neurological deficits induced by sodium nitroprusside in young mice

Dose

(mg/kg)

Gender

Period

τ (h)

Mesor ± SEM

(% of ataxia)

Amplitude ± SD

(% of ataxia)

Acrophase

±SD (min)b

Adjusted P a

 

Male

12

30 ± 4

15 ± 14

1.1 ± 120

NS

3.0

 

24

28 ± 4

2

5.4

NS

 

Female

12

33 ± 4

15 ± 14

1.2 ± 120

NS

  

24

33 ± 4

12

3.2

NS

  

12

49 ± 5

26 ± 17

1.9 ± 74

NS

3.3

Male

24

40 ± 4

10

8.8

NS

  

12

31 ± 5

17 ± 16

1.4 ± 120

NS

 

Female

24

32 ± 5

2

1.5

NS

  

12

65 ± 4

18 ± 13

1.2 ± 90

NS

3.6

 

24

64 ± 4

16 ± 13

4.5 ± 228

NS

 

Male

12

36 ± 5

16 ± 15

2.0 ± 120

NS

 

Female

24

34 ± 3

4

5.0

NS

  1. a From an F test of the rejection of the null amplitude hypothesis.
  2. b Time of maximum in fitted cosine function, in HALO.
  3. NS: Not significant