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Table 3 Parameters of circadian rhythms of sodium nitroprusside-induced motor incoordination in 8 week old mice

From: Time-of-day dependence of neurological deficits induced by sodium nitroprusside in young mice

Dose

(mg/kg)

Gender

Period

τ (h)

Mesor ±

SEM (% of ataxia)

Amplitude ± SD

(% of ataxia)

Acrophase

± SD (min)b

Adjusted P a

 

Male

12

35 ± 4

8

0.42

NS

3.0

 

24

34 ± 4

18 ± 14

3.2 ± 108

NS

 

Female

12

27 ± 4

8

2.8

NS

  

24

27 ± 4

14 ± 13

2.7 ± 78

NS

  

12

27 ± 4

8

2.7

NS

3.3

Male

24

26 ± 4

14 ± 12

2.0 ± 60

NS

  

12

19 ± 3

3

4.5

NS

 

Female

24

20 ± 3

11 ± 10

1.3 ± 90

NS

  

12

41 ± 4

6

3.1

NS

3.6

 

24

40 ± 4

23 ± 13

3.4 ± 120

0.003

 

Male

12

19 ± 3

8

1.9

NS

 

Female

24

19 ± 3

20 ± 10

2.1 ± 55

0.003

  1. a From an F test of the rejection of the null amplitude hypothesis.
  2. b Time of maximum in fitted cosine function, in HALO.
  3. NS: Not significant