From: Time-of-day dependence of neurological deficits induced by sodium nitroprusside in young mice
Dose (mg/kg) | Gender | Period τ (h) | Mesor ± SEM (% of ataxia) | Amplitude ± SD (% of ataxia) | Acrophase ± SD (min)b | Adjusted P a |
---|---|---|---|---|---|---|
Male | 12 | 35 ± 4 | 8 | 0.42 | NS | |
3.0 | 24 | 34 ± 4 | 18 ± 14 | 3.2 ± 108 | NS | |
Female | 12 | 27 ± 4 | 8 | 2.8 | NS | |
24 | 27 ± 4 | 14 ± 13 | 2.7 ± 78 | NS | ||
12 | 27 ± 4 | 8 | 2.7 | NS | ||
3.3 | Male | 24 | 26 ± 4 | 14 ± 12 | 2.0 ± 60 | NS |
12 | 19 ± 3 | 3 | 4.5 | NS | ||
Female | 24 | 20 ± 3 | 11 ± 10 | 1.3 ± 90 | NS | |
12 | 41 ± 4 | 6 | 3.1 | NS | ||
3.6 | 24 | 40 ± 4 | 23 ± 13 | 3.4 ± 120 | 0.003 | |
Male | 12 | 19 ± 3 | 8 | 1.9 | NS | |
Female | 24 | 19 ± 3 | 20 ± 10 | 2.1 ± 55 | 0.003 |