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Table 1 Studies Included

From: Polymorphisms in melatonin synthesis pathways: possible influences on depression

Study

Participants

N

% Male

Median age (range)

Diagnoses

Delayed sleep phase disorder

Cases and Controls

768

33%

35 (22-82)

DSPD or no DSPD

Sleep Clinic

Scripps sleep disorders patients

853

65%

57 (21-96)

Sleep apnea, DSPD, insomnia, etc.

MrOS

Volunteers, multi-center

2540

100%

76 (67-96)

Mixed diagnoses or none

SOF

Volunteers, multi-center

1731

0%

83 (79-99)

Mixed diagnoses or none

Bipolar disorder

VA clinic patients

80

63%

46 (21-67)

All had bipolar disorder