Figure 4
From: Chronotolerance study of the antiepileptic drug valproic acid in mice
Circadian variation in tolerance to VPA (850 mg/kg, i.p. ) as assessed by the survival rate at each of six circadian dosing-times (1, 5, 9, 13, 17, and 21 HALO) in a total of 90 mice. Results are expressed as mean percent change ± S.D and were statistically validated by χ 2 test (p ≤ 0.001).