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  1. Content type: Research

    Nitric oxide synthase (NOS) is essential for the synthesis of nitric oxide (NO), a non-conventional neurotransmitter with an important role in synaptic plasticity underlying processes of hippocampus-dependent ...

    Authors: Aline V Machado-Nils, Larissa OM de Faria, André S Vieira, Simone A Teixeira, Marcelo N Muscará and Elenice AM Ferrari

    Citation: Journal of Circadian Rhythms 2013 11:12

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  2. Content type: Research

    Mammals can adapt to changing light/dark conditions by advancing or delaying their circadian clock phase. Light pulses evoke changes in gene expression and neuronal activity in the suprachiasmatic nuclei (SCN)...

    Authors: Marie Aramendy, Sascha Seibert, Philipp Treppmann, Karin Richter, Gudrun Ahnert-Hilger and Urs Albrecht

    Citation: Journal of Circadian Rhythms 2013 11:11

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  3. Content type: Research

    Although out-of-lab investigation of the human circadian clock at the clock gene expression level remains difficult, a recent method using hair follicle cells might be useful. While exercise may function as an...

    Authors: Akihiko Okamoto, Takuro Yamamoto, Ritsuko Matsumura, Koichi Node and Makoto Akashi

    Citation: Journal of Circadian Rhythms 2013 11:10

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  4. Content type: Research

    Our recent studies demonstrate that the murine homolog of the human tumor suppressor promyelocytic leukemia (PML) regulates circadian behavior of mice. To further gather insight into PML’s contribution to circ...

    Authors: Takao Miki, Misty Chen-Goodspeed, Zhaoyang Zhao and Cheng Chi Lee

    Citation: Journal of Circadian Rhythms 2013 11:9

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  5. Content type: Research

    Intracellular calcium is a biochemical messenger that regulates part of the metabolic adaptations in the daily fed-fast cycle. The aim of this study was to characterize the 24-h variations of the liver ryanodi...

    Authors: Adrián Báez-Ruiz, Karina Cázares-Gómez, Olivia Vázquez-Martínez, Raúl Aguilar-Roblero and Mauricio Díaz-Muñoz

    Citation: Journal of Circadian Rhythms 2013 11:8

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  6. Content type: Research

    Epidemiological studies in Japan have documented an association between morning type and a tryptophan-rich breakfast followed by exposure to sunlight in children. The association may be mediated by enhanced me...

    Authors: Kai Wada, Shota Yata, Osami Akimitsu, Milada Krejci, Teruki Noji, Miyo Nakade, Hitomi Takeuchi and Tetsuo Harada

    Citation: Journal of Circadian Rhythms 2013 11:4

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  7. Content type: Research

    There are several indications that malfunctions of the circadian clock contribute to depression. To search for particular circadian gene polymorphisms associated with depression, diverse polymorphisms were gen...

    Authors: Daniel F Kripke, Caroline M Nievergelt, Gregory J Tranah, Sarah S Murray, Katharine M Rex, Alexandra P Grizas, Elizabeth K Hahn, Heon-Jeong Lee, John R Kelsoe and Lawrence E Kline

    Citation: Journal of Circadian Rhythms 2013 11:3

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  8. Content type: Research

    The relation between circadian dysregulation and cancer incidence and progression has become a topic of major interest over the last decade. Also, circadian timing has gained attention regarding the use of chr...

    Authors: Natalia Paladino, José M Duhart, Malena L Mul Fedele and Diego A Golombek

    Citation: Journal of Circadian Rhythms 2013 11:2

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  9. Content type: Research

    A comprehensive understanding of the equine circadian clock involves the evaluation of circadian clock gene expression. A non-invasive and effective method for detecting equine clock gene expression has yet to...

    Authors: Lisa M Watts, John A Browne and Barbara A Murphy

    Citation: Journal of Circadian Rhythms 2012 10:7

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  10. Content type: Research

    An endogenous circadian clock controls locomotor activity in common spiny mice (Acomys cahirinus). However, little is known about the effects of constant light (LL) on this activity or about the existence of a...

    Authors: Christopher C Chabot, Devin M Connolly and Brenda B Waring

    Citation: Journal of Circadian Rhythms 2012 10:6

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  11. Content type: Research

    Metallothionein (MT) is a small, cysteine-rich, metal-binding protein that plays an important role in protecting against toxicity of heavy metal and chemicals. This study was aimed to define diurnal and sex va...

    Authors: Dan Zhang, Tao Jin, Yi-qiao Xu, Yuan-Fu Lu, Qin Wu, Yu-Kun Jennifer Zhang and Jie Liu

    Citation: Journal of Circadian Rhythms 2012 10:5

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  12. Content type: Research

    Recent studies on humans and rodents have suggested that the timing of food intake plays an important role in circadian regulation and metabolic health. Consumption of high-fat foods during the inactive period...

    Authors: Yuta Fuse, Akiko Hirao, Hiroaki Kuroda, Makiko Otsuka, Yu Tahara and Shigenobu Shibata

    Citation: Journal of Circadian Rhythms 2012 10:4

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  13. Content type: Research

    Valproic acid (VPA) is an antiepileptic drug widely used for the treatment of absence seizures and generalized tonic-clonic seizures. The present work aims to study whether VPA-induced toxicity varies accordin...

    Authors: Wafa Ben-Cherif, Ichrak Dridi, Karim Aouam, Mossadok Ben-Attia, Alain Reinberg and Naceur A Boughattas

    Citation: Journal of Circadian Rhythms 2012 10:3

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  14. Content type: Research

    Physical activity as measured by activity counts over short time intervals across a 24 h period are often used to assess circadian variation. We are interested in characterizing circadian patterns in activity ...

    Authors: Semhar Ogbagaber, Paul S Albert, Daniel Lewin and Ronald J Iannotti

    Citation: Journal of Circadian Rhythms 2012 10:2

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  15. Content type: Research

    Menopause-associated thermoregulatory dysfunction can lead to symptoms such as hot flushes severely impairing quality of life of affected women. Treatment effects are often assessed by the ovariectomized rat m...

    Authors: Dorothee Girbig, Karsten Keller, Katja Prelle, Vladimir Patchev, Richardus Vonk and Bernd-Wolfgang Igl

    Citation: Journal of Circadian Rhythms 2012 10:1

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  16. Content type: Research

    The Magel2 gene is most highly expressed in the suprachiasmatic nucleus of the hypothalamus, where its expression cycles in a circadian pattern comparable to that of clock-controlled genes. Mice lacking the Magel...

    Authors: Julia Devos, Sara V Weselake and Rachel Wevrick

    Citation: Journal of Circadian Rhythms 2011 9:12

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  17. Content type: Research

    Actigraphy provides a way to objectively measure activity in human subjects. This paper describes a novel family of statistical methods that can be used to analyze this data in a more comprehensive way.

    Authors: Jia Wang, Hong Xian, Amy Licis, Elena Deych, Jimin Ding, Jennifer McLeland, Cristina Toedebusch, Tao Li, Stephen Duntley and William Shannon

    Citation: Journal of Circadian Rhythms 2011 9:11

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  18. Content type: Research

    Many previous studies have documented seasonal variation in suicides globally. We re-assessed the seasonal variation of suicides in Finland and tried to relate it to the seasonal variation in daylength and amb...

    Authors: Laura Hiltunen, Kirsi Suominen, Jouko Lönnqvist and Timo Partonen

    Citation: Journal of Circadian Rhythms 2011 9:10

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  19. Content type: Research

    In university health care settings, students with psychosomatic complaints often have chronotypic problems. For this reason, we investigated a potential connection between psychosomatic complaints and circadia...

    Authors: Mitsuo Nagane, Rie Suge and Shu-Ichi Watanabe

    Citation: Journal of Circadian Rhythms 2011 9:9

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  20. Content type: Research

    It has been reported that rs4446909, a single nucleotide polymorphism (SNP) in the promoter of acetylserotonin methyltransferase (ASMT), influences the expression of the ASMT enzyme. The common G allele is associ...

    Authors: Daniel F Kripke, Caroline M Nievergelt, Greg J Tranah, Sarah S Murray, Michael J McCarthy, Katharine M Rex, Neeta Parimi and John R Kelsoe

    Citation: Journal of Circadian Rhythms 2011 9:8

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