Figure 4From: Standards of evidence in chronobiology: critical review of a report that restoration of Bmal1 expression in the dorsomedial hypothalamus is sufficient to restore circadian food anticipatory rhythms in Bmal1-/- mice The thermogenic effect of midday feeding in rats (R. Mistlberger, B. Kent, G. Landry, unpublished). Group mean average waveforms of core body temperature measured via implanted transponders in rats (N = 11) under adlib food access (thin black line), 4 h/day restricted feeding (heavy line = day1, heavy green line = day 21), and total food deprivation (heavy red line = day1). Temperature rises dramatically within 10 min of meal onset on days 1 and 21 of restricted feeding, and remains elevated throughout mealtime on the meal omission day after day 21.Back to article page