Figure 5From: Standards of evidence in chronobiology: critical review of a report that restoration of Bmal1 expression in the dorsomedial hypothalamus is sufficient to restore circadian food anticipatory rhythms in Bmal1-/- mice The thermogenic effect of midday feeding in mice, adapted from Moriya et al [16]. Group mean average waveforms of core body temperature measured via implanted transponders in mice (sham lesion = open circles, DMH lesion = closed circles) under 4 h/day restricted feeding in LD (days 2 and 13) and total food deprivation in DD. Temperature rises dramatically within 15 min of meal onset on days 2 and 13 of restricted feeding, and remains elevated throughout mealtime on the meal omission day.Back to article page