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  1. "Minimal (subclinical) hepatic encephalopathy" is a term that describes impairment of every day life activities in cirrhosis patients without clinical neurologic abnormalities. Melatonin diurnal pattern disrup...

    Authors: Dimitrios Velissaris, Vasilis Karamouzos, Panagiotis Polychronopoulos and Menelaos Karanikolas

    Citation: Journal of Circadian Rhythms 2009 7:6

    Content type: Research

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  2. Mammalian circadian clocks control multiple physiological events. The principal circadian clock generates seasonal variations in behavior as well. Seasonality elevates the risk for metabolic syndrome, and evid...

    Authors: Ani Englund, Leena Kovanen, Sirkku T Saarikoski, Jari Haukka, Antti Reunanen, Arpo Aromaa, Jouko Lönnqvist and Timo Partonen

    Citation: Journal of Circadian Rhythms 2009 7:5

    Content type: Research

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  4. Daily feeding schedules generate food anticipatory rhythms of behavior and physiology that exhibit canonical properties of circadian clock control. The molecular mechanisms and location of food-entrainable cir...

    Authors: Ralph E Mistlberger, Ruud M Buijs, Etienne Challet, Carolina Escobar, Glenn J Landry, Andries Kalsbeek, Paul Pevet and Shigenobu Shibata

    Citation: Journal of Circadian Rhythms 2009 7:3

    Content type: Review

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  5. Clinical symptoms of affective disorders, their response to light treatment, and sensitivity to other circadian interventions indicate that the circadian system has a role in mood disorders. Possibly the mecha...

    Authors: Daniel F Kripke, Caroline M Nievergelt, EJ Joo, Tatyana Shekhtman and John R Kelsoe

    Citation: Journal of Circadian Rhythms 2009 7:2

    Content type: Research

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  7. Night work is associated with disturbed sleep and wakefulness, particularly in relation to the night shift. Circadian rhythm sleep disorders are characterized by complaints of insomnia and excessive daytime sl...

    Authors: Khosro Sadeghniiat-Haghighi, Omid Aminian, Gholamreza Pouryaghoub and Zohreh Yazdi

    Citation: Journal of Circadian Rhythms 2008 6:10

    Content type: Research

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  8. The central circadian pacemaker is a remarkably robust regulator of daily rhythmic variations of cardiovascular, endocrine, and neural physiology. Environmental lighting conditions are powerful modulators of c...

    Authors: He Meng, Tiecheng Liu, Jimo Borjigin and Michael M Wang

    Citation: Journal of Circadian Rhythms 2008 6:9

    Content type: Research

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  9. Variation in circadian rhythms and nocturnality may, hypothetically, be related to or independent of genetic variation in photoperiodic mediation of seasonal changes in physiology and behavior. We hypothesized...

    Authors: Cheryl D Seroka, Cynthia E Johnson and Paul D Heideman

    Citation: Journal of Circadian Rhythms 2008 6:8

    Content type: Research

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  11. Delayed sleep phase disorder (DSPD) is a condition in which patients have difficulty falling asleep before the early morning hours and commonly have trouble awakening before late morning or even early afternoo...

    Authors: Daniel F Kripke, Katharine M Rex, Sonia Ancoli-Israel, Caroline M Nievergelt, Walt Klimecki and John R Kelsoe

    Citation: Journal of Circadian Rhythms 2008 6:6

    Content type: Research

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  12. Circadian organisation of behavioural and physiological rhythms in mammals is largely driven by the clock in the suprachiasmatic nuclei (SCN) of the hypothalamus. In this clock, a molecular transcriptional rep...

    Authors: Daan R van der Veen, Ellis GA Mulder, Henrik Oster, Menno P Gerkema and Roelof A Hut

    Citation: Journal of Circadian Rhythms 2008 6:5

    Content type: Research

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  13. Previous reports have suggested that the ablation of the Period 2 gene (Per 2) leads to enhanced development of lymphoma and leukemia in mice. Employing immunoblot analyses, we have demonstrated that PER 2 is end...

    Authors: Shulin Xiang, Seth B Coffelt, Lulu Mao, Lin Yuan, Qi Cheng and Steven M Hill

    Citation: Journal of Circadian Rhythms 2008 6:4

    Content type: Research

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  14. The plant circadian clock has at its core a feedback loop that includes TIMING OF CAB2 EXPRESSION 1 (TOC1). This protein has an as of yet unknown biochemical activity. It has been noted that the extreme amino-...

    Authors: Elsebeth Kolmos, Heiko Schoof, Michael Plümer and Seth J Davis

    Citation: Journal of Circadian Rhythms 2008 6:3

    Content type: Research

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  15. Anopheles gambiae s.s. Giles is a major malaria vector in Sub-Saharan Africa. Studies of the basic biology of this mosquito, including oviposition, provide a background for assessing which attr...

    Authors: Megan L Fritz, Juan Huang, Edward D Walker, M Nabie Bayoh, John Vulule and James R Miller

    Citation: Journal of Circadian Rhythms 2008 6:2

    Content type: Research

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  16. The absence of circadian zeitgebers in the social environment causes circadian misalignment, which is often associated with sleep disturbances. Circadian misalignment, defined as a mismatch between the sleep-w...

    Authors: Girardin Jean-Louis, Ferdinand Zizi, Douglas R Lazzaro and Arthur H Wolintz

    Citation: Journal of Circadian Rhythms 2008 6:1

    Content type: Review

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  17. Many genes control circadian period in mice. Prior studies suggested a quantitative trait locus (QTL) on proximal mouse chromosome 12 for interstrain differences in circadian period. Since the B6.D2NAhr ...

    Authors: John R Hofstetter, Doreen A Svihla-Jones and Aimee R Mayeda

    Citation: Journal of Circadian Rhythms 2007 5:7

    Content type: Research

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  18. An adriamycin-induced impairment of wound healing has been demonstrated experimentally in rats. The purpose of this study is to investigate a possible temporal variation in recovery from the impairment of woun...

    Authors: Haluk Alagol, Soykan Dinc, Bilgen Basgut and Nurettin Abacioglu

    Citation: Journal of Circadian Rhythms 2007 5:6

    Content type: Research

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  19. Rapid displacement across multiple time zones results in a conflict between the new cycle of light and dark and the previously entrained program of the internal circadian clock, a phenomenon known as jet lag. ...

    Authors: Barbara A Murphy, Jeffrey A Elliott, Dawn R Sessions, Mandi M Vick, Erin L Kennedy and Barry P Fitzgerald

    Citation: Journal of Circadian Rhythms 2007 5:5

    Content type: Research

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  21. Bipolar disorder (BPD) is a widespread condition characterized by recurring states of mania and depression. Lithium, a direct inhibitor of glycogen synthase kinase 3 (GSK3) activity, and a mainstay in BPD ther...

    Authors: Sevag A Kaladchibachi, Brad Doble, Norman Anthopoulos, James R Woodgett and Armen S Manoukian

    Citation: Journal of Circadian Rhythms 2007 5:3

    Content type: Research

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  22. The effects of lighting on the human circadian system are well-established. The recent discovery of 'non-visual' retinal receptors has confirmed an anatomical basis for the non-image forming, biological effect...

    Authors: Peter R Mills, Susannah C Tomkins and Luc JM Schlangen

    Citation: Journal of Circadian Rhythms 2007 5:2

    Content type: Research

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  23. We recently reported that the altitude of origin altered the photic and thermal sensitivity of the circadian pacemaker controlling eclosion and oviposition rhythms of high altitude Himalayan strains of Drosophila...

    Authors: Keny Vanlalhriatpuia, Vanlalnghaka Chhakchhuak, Satralkar K Moses, SB Iyyer, MS Kasture, AJ Shivagaje, Barnabas J Rajneesh and Dilip S Joshi

    Citation: Journal of Circadian Rhythms 2007 5:1

    Content type: Research

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  24. In domestic animals many biochemical and physiological processes exhibit daily rhythmicity. The aim of the present study was to investigate the rhythmic pattern of salivary and serum urea concentrations in sheep.

    Authors: Giuseppe Piccione, Augusto Foà, Cristiano Bertolucci and Giovanni Caola

    Citation: Journal of Circadian Rhythms 2006 4:16

    Content type: Short paper

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  25. Recent studies have implicated the epidermal growth factor receptor (EGFR) within the subparaventricular zone as being a major mediator of locomotor and masking behaviors in mice. The results were based on sma...

    Authors: Reade B Roberts, Carol L Thompson, Daekee Lee, Richard W Mankinen, Aziz Sancar and David W Threadgill

    Citation: Journal of Circadian Rhythms 2006 4:15

    Content type: Short paper

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  26. The human body exhibits a variety of biological rhythms. There are patterns that correspond, among others, to the daily wake/sleep cycle, a yearly seasonal cycle and, in women, the menstrual cycle. Sine/cosine...

    Authors: Naser B Elkum and James D Myles

    Citation: Journal of Circadian Rhythms 2006 4:14

    Content type: Research

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  27. Although the number of circulating immune cells is subject to high-amplitude circadian rhythms, the underlying mechanisms are not fully understood.

    Authors: Katsutaka Oishi, Naoki Ohkura, Koji Kadota, Manami Kasamatsu, Kentaro Shibusawa, Juzo Matsuda, Kazuhiko Machida, Shuichi Horie and Norio Ishida

    Citation: Journal of Circadian Rhythms 2006 4:13

    Content type: Research

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  29. Biological rhythmicity, particularly circadian rhythmicity, is considered to be a key mechanism in the maintenance of physiological function. Very little is known, however, about biological rhythmicity pattern...

    Authors: Esmot ara Begum, Motoki Bonno, Makoto Obata, Hatsumi Yamamoto, Masatoshi Kawai and Yoshihiro Komada

    Citation: Journal of Circadian Rhythms 2006 4:11

    Content type: Research

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  30. Measurement of locomotor activity is a valuable tool for analysing factors influencing behaviour and for investigating brain function. Several methods have been described in the literature for measuring the am...

    Authors: Jean-Etienne Poirrier, Laurent Poirrier, Pierre Leprince and Pierre Maquet

    Citation: Journal of Circadian Rhythms 2006 4:10

    Content type: Research

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  31. Every physiological function in the human body exhibits some form of circadian rhythmicity. Under pathological conditions, however, circadian rhythmicity may be dusrupted. Patients infected with HIV or addicte...

    Authors: Xiaojia Wang, Yueqi Wang, Haoyang Xin, Yanyou Liu, Yuhui Wang, Hang Zheng, Zhou Jiang, Chaomin Wan, Zhengrong Wang and Jian M Ding

    Citation: Journal of Circadian Rhythms 2006 4:9

    Content type: Research

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  32. The aim of the study was to examine the role that melatonin production plays in the regulation of sleep consolidation in a population of shiftworkers working and sleeping in their natural environments.

    Authors: Gregory D Roach, Kathryn J Reid, Sally Ferguson and Drew Dawson

    Citation: Journal of Circadian Rhythms 2006 4:8

    Content type: Short paper

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  34. We have recently reported that spontaneous internal desynchronization between the locomotor activity rhythm and the melatonin rhythm may occur in rats (30% of tested animals) when they are maintained in consta...

    Authors: Jacopo Aguzzi, Nicole M Bullock and Gianluca Tosini

    Citation: Journal of Circadian Rhythms 2006 4:6

    Content type: Research

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  35. A stable and systematic daily change in light levels at dawn and dusk provides the most reliable indicator of the phase of the day. It is likely that organisms have evolved mechanisms to use these twilight tra...

    Authors: Amit K Trivedi, Sangeeta Rani and Vinod Kumar

    Citation: Journal of Circadian Rhythms 2006 4:5

    Content type: Research

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  37. This work addresses the issue of whether methoxychlor (MTX) exposure may modify the ultradian secretion of prolactin through changes in the synthesis of nitric oxide (NO) induced by Nω-nitro-L-arginine methyl est...

    Authors: Anunciación Lafuente, Teresa Cabaleiro, Pilar Cano and Ana I Esquifino

    Citation: Journal of Circadian Rhythms 2006 4:3

    Content type: Research

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  38. There has been extensive research in the recent past looking into the molecular basis and mechanisms of the biological clock, situated in the suprachiasmatic nuclei (SCN) of the anterior hypothalamus. Neurotra...

    Authors: Vallath Reghunandanan and Rajalaxmy Reghunandanan

    Citation: Journal of Circadian Rhythms 2006 4:2

    Content type: Review

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  39. Daylight saving time is widely adopted. Little is known about its influence on the daily rest-activity cycles. We decided to explore the effects of transition into daylight saving time on the circadian rhythm ...

    Authors: Tuuli A Lahti, Sami Leppämäki, Sanna-Maria Ojanen, Jari Haukka, Annamari Tuulio-Henriksson, Jouko Lönnqvist and Timo Partonen

    Citation: Journal of Circadian Rhythms 2006 4:1

    Content type: Research

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  40. Some medical disorders have higher prevalence in shift workers than others. This study was designed to evaluate the effect of night-shift-working on total plasma antioxidant capacity, with respect to the causa...

    Authors: Akbar Sharifian, Saeed Farahani, Parvin Pasalar, Marjan Gharavi and Omid Aminian

    Citation: Journal of Circadian Rhythms 2005 3:15

    Content type: Short paper

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  41. It is well established that the absolute sensitivity of the suprachiasmatic nucleus to photic stimulation received through the retino-hypothalamic tract changes throughout the 24-hour day. It is also believed ...

    Authors: Mariana G Figueiro, John D Bullough, Robert H Parsons and Mark S Rea

    Citation: Journal of Circadian Rhythms 2005 3:14

    Content type: Research

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  42. Ocular pathology lessens light's efficacy to maintain optimal circadian entrainment. We examined whether ophthalmic dysfunction explains unique variance in melatonin excretion of older adults over and above th...

    Authors: Girardin Jean-Louis, Daniel F Kripke, Jeffrey A Elliott, Ferdinand Zizi, Arthur H Wolintz and Douglas R Lazzaro

    Citation: Journal of Circadian Rhythms 2005 3:13

    Content type: Research

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  43. Responsiveness to changing photoperiods from summer to winter seasons is an important but variable physiological trait in most temperate-zone mammals. Variation may be due to disorders of melatonin secretion o...

    Authors: Matthew Rocco Price, Julie Anita Marie Kruse, M Eric Galvez, Annaka M Lorincz, Mauricio Avigdor and Paul D Heideman

    Citation: Journal of Circadian Rhythms 2005 3:12

    Content type: Research

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  44. Our aims were to examine the influence of different bright light schedules on mood, sleep, and circadian organization in older adults (n = 60, ages 60–79 years) with insomnia and/or depression, contrasting wit...

    Authors: Shawn D Youngstedt, Daniel F Kripke, Jeffrey A Elliott and Katharine M Rex

    Citation: Journal of Circadian Rhythms 2005 3:11

    Content type: Research

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  46. This work describes the effect of a 48-h litter separation on 24-h patterns of plasma prolactin, FSH and LH concentration in female lactating rabbits kept under a 16:8 light-dark photoperiod (lights on at 0800...

    Authors: Pilar Cano, Vanessa Jiménez, Maria P Álvarez, Mario Alvariño, Daniel P Cardinali and Ana I Esquifino

    Citation: Journal of Circadian Rhythms 2005 3:9

    Content type: Research

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  47. We observed that a dim, red light-emitting diode (LED) triggered by activity increased the circadian periods of lab mice compared to constant darkness. It is known that the circadian period of rats increases w...

    Authors: John R Hofstetter, Amelia R Hofstetter, Amanda M Hughes and Aimee R Mayeda

    Citation: Journal of Circadian Rhythms 2005 3:8

    Content type: Research

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  48. Circadian clocks are believed to have evolved in parallel with the geological history of the earth, and have since been fine-tuned under selection pressures imposed by cyclic factors in the environment. These ...

    Authors: Dhanashree A Paranjpe and Vijay Kumar Sharma

    Citation: Journal of Circadian Rhythms 2005 3:7

    Content type: Review

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  49. The serotonergic system is associated with numerous brain functions, including the resetting of the mammalian circadian clock. The synthesis and metabolism of 5-HT in the brain increases in response to exercis...

    Authors: Giuseppe Piccione, Anna Assenza, Francesco Fazio, Maurizio Percipalle and Giovanni Caola

    Citation: Journal of Circadian Rhythms 2005 3:6

    Content type: Short paper

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  50. Very little is known about the perinatal genesis of circadian rhythmicity in the human fetus. Some researchers have found evidence of rhythmicity early on in fetal development, whereas others have observed a s...

    Authors: Paliko I Kintraia, Medea G Zarnadze, Nicolas P Kintraia and Ia G Kashakashvili

    Citation: Journal of Circadian Rhythms 2005 3:5

    Content type: Research

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Journal of Circadian Rhythms

ISSN: 1740-3391